PanTum® Detect blood test uses the proprietary German EDIM technology that leverages our innate immune system to distinguish between silently growing pre-cancerous (benign) and malignant tumor growth independent of tumor entity.
Macrophages are a type of white blood cells that function as a component of our innate immune system. They are differentiated monocytes that turn into macrophages to fight invading germs (viruses, bacteria, fungi, protozoa etc.) that enter the human body.
Macrophage cells surround the invading germ, ingest, and kill it with enzymes within the cell. Macrophages “eat the tumor cell” as part of its scavenging function and thus play a crucial role in defending humans from the invading dangerous tumor cells.
PanTum® Detect uses a proprietary EDIM (Epitope Detection in Monocytes) Technology developed by Zyagnum AG, a German bio-tech company, for intracellular detection of “pan- tumor” enzyme biomarkers DNaseX (Apo10) & TKTL1 in macrophages.
The joint use of DNaseX (Apo10) & TKTL1 distinguishes between benign/ pre-cancerous and malignant tumor growth, independent of tumor entity. While DNaseX (Apo10) can be found in all pre-cancerous (benign) and malignant tumor cells, TKTL1 is detectable in all malignant/cancer cells. The expression of TKTL1 initiates diverse stages of malignancy progression and provides earliest possible indication of a malignant tumor growth.